Abstract: I will explore the promising potential of blazars — active galactic nuclei with relativistic jets pointed towards Earth — as ideal laboratories for studying sub-GeV Dark Matter phenomenology. Specifically, I will discuss how blazar-boosted Dark Matter could be detected by neutrino experiments, as well as the recently proposed idea that the 2017 detection of a high-energy neutrino from the blazar TXS 0506+056 — the first association of one such event with an astrophysical source — may be attributed to proton-Dark Matter interactions. In fact, while astrophysical models of the blazar’s jet explain its electromagnetic emissions across a vast range of energies, they fall short by roughly two orders of magnitude in reproducing the observed neutrino flux.